疏风宣肺汤治疗咳嗽变异性哮喘风邪犯肺证 42例疗效观察

林鸿春¹  李楠^2△  焦扬²  蔡玲玲²

（1.北京市昌平区中医医院，北京，102200；2.北京中医药大学东方医院，北京，100078）

中图分类号：R256.12    文献标识码：A    文章编号：1674-7860（2016）15-0012-03    证型：GDI

【摘  要】目的：观察疏风宣肺汤治疗咳嗽变异性哮喘（CVA）风邪犯肺证的临床疗效。方法：将42例辨证为风邪犯肺证的CVA患者随机分为治疗组及对照组，两组采用相同基础用药，治疗组在基础用药同时加用疏风宣肺汤加减口服，疗程2周，疗程结束后评估临床疗效及安全性。结果：中医证候疗效比较，治疗组总有效率为90.5%，对照组57.1%，有显著性差异（P＜0.05）；两组咳嗽频率积分、咳嗽程度积分、总积分比较，治疗组较对照组明显降低，差异有统计学意义（P＜0.05）；两组外周血嗜酸性粒细胞计数比较P=0.610＞0.05，差异无统计学意义。两组均无严重不良反应发生。结论：疏风宣肺汤参加减参与治疗咳嗽变异性哮喘（CVA）风邪犯肺证能显著提高临床疗效，安全可靠。

【关键词】疏风宣肺汤；咳嗽变异性哮喘；风邪犯肺证；疗效观察

【Abstract】Objective：To observethe clinical efficacy of Shufeng Xuanfei Decoction in the treatment of thesyndrome of pathogenic wind attacking lung with cough variant asthma (CVA).Methods：42 patients of the syndrome of pathogenic wind attacking lung withCVA were randomly divided into the treatment group and the control group. Allpatients were treated with the conventional therapy, and the treatment groupwas additionally treated with Shufeng Xuanfei Decoction. The clinical efficacyand safety was evaluated 2 weeks after the treatment．Results:Comparison of the efficacy of TCM syndrome showed that the total efficiency inthe treatment group was 90.5% and that in the control group was 57.1%, thedifference was statistically significant (P<0.05).The cough frequency integral, cough degree integral and total integral weresignificantly lower in the treatment group than the control group after 2weeks, the difference was statistically significant (P<0.05). Comparison of the peripheral eosinophil count depictedthat there was no statistical significance between the treatment group and thecontrol group (P<0.05). No severeadverse effects were found during treatment. Conclusion: Shufeng XuanfeiDecoction in the treatment of patients with the syndromeof pathogenic wind attacking lung with CVA can significantly improve theclinical efficacy, and it is very safe too.

【Keywords】ShufengXuanfei Decoction; Cough variant asthma; Syndrome of pathogenic wind attackinglung; Clinical efficacy

doi:10.3969/j.issn.1674-7860.2016.15.006

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作者简介：

林鸿春，男，汉族，硕士，主治医师，2013—2015年参加昌平区中医医院“北京中医药传承3+3工程基层老中医传承工作室”工作，师承名老中医李葆富。2015年12月起参加北京中医药传承“双百工程”学习，师承东直门医院名老中医孙霈。E-mail：13810111769@139.com。

李楠，通讯作者，女，主治医师，博士，工作于北京中医药大学东方医院皮肤科，研究方向：主要治疗变态反应性疾病及感染性皮肤病。