加味黄芪桂枝五物汤治疗狼疮性肾炎激素撤减期 的效果探讨

加味黄芪桂枝五物汤治疗狼疮性肾炎激素撤减期

柏林¹  刘崇俊²

（1.大连市第五人民医院，辽宁  大连，116021；2.大连市中医医院，辽宁  大连，116021）

中图分类号：R256.5     文献标识码：A    文章编号：1674-7860（2016）09-0087-02   证型：IDGB

【摘  要】目的：分析加味黄芪桂枝五物汤治疗狼疮性肾炎激素撤减期的临床疗效。方法：选择我院2014年2月—2015年3月在我院所接受治疗的狼疮性肾炎患者120例作为研究对象，随机分为实验组和常规组各60例。常规组使用常规的治疗方式，实验组则使用加味黄芪桂枝五物汤进行治疗。结果：常规组与实验组经过治疗之后的各项身体指标与治疗之前无明显差异，不具备统计学意义（P＞0.05）。实验组与常规组患者经过治疗之后，实验组患者的所有身体指标均明显高于常规组患者，肾功能、动态血沉、超敏C-反应蛋白、24 h尿蛋白量这4项数据差异显著，具备统计学意义（P＜0.05）。结论：加味黄芪桂枝五物汤治疗狼疮性肾炎激素撤减期的临床疗效显著，帮助患者消除狼疮性肾炎激素撤减期所出现的各项病情复发可能性，值得临床推广。

【关键词】加味黄石桂枝五物汤；狼疮性肾炎激素撤减期；疗效

【Abstract】Objective: To explore and analyze theclinical curative effect of Jiawei Huangqi Guizhi Wuwu Decoction in treating lupusnephritis in hormone withdrawal period. Methods: 120 patients with lupus nephritis,who were admitted and treated in our hospital form February 2014 to March 2015,were selected and randomly divided into the control group and the experimentgroup, with 60 cases in each group, the control group received conventionalroutine treatment while the experiment group received Jiawei Huangqi Guizhi WuwuDecoction. Results: After treatment, there was no significant difference of thebody indexes of patients in two groups compared with those before thetreatment, the difference was of no statistical significance (P＞0.05). After treatment, the body indexes ofpatients in the experiment group were significantly better than those of thecontrol group, there was significant difference in renal function, ESR, highsensitivity C reactive protein, 24h urinary protein, the difference was ofstatistical significance (P＞0.05). Conclusion:Jiawei Huangqi Guizhi Wuwu Decoction had significant clinicalcurative effect in treating lupus nephritis in hormone withdrawal period, itcould eliminate the possibility of recurrence of the disease of lupus nephritisin hormone withdrawal period and was worthy of clinical promotion.

【Keywords】Jiawei Huangqi Guizhi Wuwu Decoction; lupusnephritis in hormone withdrawal period; curative effect

doi:10.3969/j.issn.1674-7860.2016.09.040

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