高血压病患者脉象参数与血压变异性的相关研究　

魏世超^1,2 张林香³郑星宇^1,2   薛飞龙²  骆杰伟^1,2  郭苗苗²  孟晓嵘^1,2  黄昉萌^1,2

   （1.福建医科大学省立临床学院，福建  福州，350001；2.福建省立医院，福建  福　州，350001； 3.龙岩市第二医院，福建  龙岩，364000）

中图分类号：R541.4   文献标识码：A    文章编号：1674-7860(2015)30-0023-06    证型：BDG

【摘  要】目的：探讨高血压病（EH）脉象参数与血压变异性（BPV）的相关性。方法：收集高血压病130例的脉象参数（DDMX-100脉象仪）及24 h动态血压数据，计算BPV。结果：偏相关分析显示，调整年龄、体重指数等影响因素后，24 h SBP与h 3、h 3/h 1、h 4/h 1、W 1、As、Ad呈负相关，r分别-0.294、-0.327、-0.382、-0.348、-0.177、-0.289（P＜0.05），而h 5/h 1与24 h SBP、24 h DBP呈正相关，r分别为0.207、0.192（P＜0.05）；PP与h 3、h 3/h 1、h 4/h 1、W 1、As、Ad呈负相关，r分别为-0.322、-0.373、-0.385、-0.323、-0.218、-0.274（P＜0.05）；24 h SBPSD与h 4/h 1、Ad呈负相关（r = -0.264、-0.269，P＜0.01）；24 h SBPL与h 3、h 3/h 1、h 4/h 1、W 1、As、Ad呈负相关（r = -0.399、-0.380、-0.478、-0.385、-0.276、-0.428，P＜0.01）。结论：血压变异性（BPV）影响了高血压病的脉象构成。

【关键词】高血压病；血压变异性；脉象

【Abstract】Objective:To study and explore the correlation betweenpulse parameters and blood pressure variability (BPV) inessential hypertension (EH). Methods: Data of Pulse parameters by DDMX-100 electropulsograph and24-hour ambulatoryblood pressures was collected from 130 cases, and blood pressure variability(BPV) was calculated accordingly.Results: Partial correlation analyses showedas follows: 24hSBP (24h mean systolic blood pressure) was negatively correlatedwith h3 (tide wave height), h3/h1(principalwave height), h4(dicrotic notch height)/h1, W1(pulse diagram width above 1/3h1), As (systole area) and Ad (diastolearea) (respectively, r = -0.294, -0.327,-0.382, -0.348, -0.177, -0.289, P<0.05），while 24hSBP, 24hDBP (24h mean diastolic blood pressure)was positively correlated with h5 (repulsewave height) /h1 (respectively, r =0.207, 0.192,P<0.05). PP (Pulse pressure)was negatively correlated with h3, h3/h1, h4/h1, W1, As and Ad (respectively,r = -0.322,-0.373, -0.385, -0.323, -0.218, -0.274,P<0.05). 24hSBPSD (24hSBP Standard deviation) was negativelycorrelated with h4/h1, As and Ad (respectively, r = -0.264, 0.269，P<0.01). 24hSBPL (24hSBP load) was negatively correlatedwith h3, h3/h1, h4/h1, W1, As, Ad(respectively,r= -0.399, -0.380, -0.478, -0.385, -0.276, -0.428，P<0.01）. Conclusion: Blood pressure variability(BPV) leads to pulse variety of EH.

【Keywords】Essential hypertension; Blood pressure variability;Pulse Condition

doi:10.3969/j.issn.1674-7860.2015.30.012

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