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依那普利与丹参酮对肺心病急性加重期患者血液流变学及心功能的改善作用分析

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梁志诚    

(日照市中医医院,山东  日照,276800

类号:R256.22    献标识码:A    文章编号:1674-7860(2016)18-0114-03    :BDG

【摘  要】目的:探讨依那普利与丹参酮联合治疗肺心病急性加重期(AECPHD)的疗效及对患者血液流变学、心功能的影响。方法:84AECPHD患者随机分为观察组与对照组,各42例。对照组予以依那普利口服,观察组在对照组的基础上予以丹参酮治疗,对比两组的疗效、血液流变学指标及心功能指标变化。结果:观察组的总有效率为95.2%,显著高于对照组的81.0%P0.05);治疗后观察组的LVEFCOSV均显著高于对照组,mPVPWBHSVWBLSVPVHCTFg显著低于对照组(P0.05)。结论:依那普利与丹参酮联合治疗AECPHD能够有效改善患者的血液流变学状态及心功能,提高临床疗效,且药物不良反应能够耐受。

【关键词】肺心病;急性加重期;依那普利;丹参酮;血液流变学;心功能

AbstractObjective:To investigate the efficacy and effect of enalapril and tanshinonon hemorheological and cardiac function of patients with acute exacerbation ofchronic pulmonary heart disease (AECPHD). Methods:84cases of AECPHD patients were randomLy divided into the observation group andthe control group, with 42 cases in each group. The control group received oraladministration of enalapril while the observation group received tanshinontreatment on the basis of the treatment of the control group. The efficacy,changes of the hemorheology and heart function indexes of the two groups wascompared. Results: The total effective rate of the observation group was 95.2%,which was significantly higher than that of the control group (P<0.05); After treatment, the LVEF,CO and SV of the observation group were significantly higher than that of thecontrol group, mPVP, WBHSV, WBLSV, PV, HCT and Fg of the observation group weresignificantly lower than that of the control group (P<0.05). Conclusions:Thecombined treatment of enalapril and tanshinon could improve the hemorheologystatus and cardiac function of AECHPD patients, it could promote the clinicalefficacy, and the adverse reactions could be tolerated.

KeywordsChronic pulmonary heart disease; Acuteexacerbation; Enalapril; Tanshinon; Hemorheology; Cardiac function

doi:10.3969/j.issn.1674-7860.2016.18.055


详情请浏览《中医临床研究》2016第18期‍

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