张玲1 蔡玲玲2 李元文2*
中图分类号：R758.24 文献标识码：A 文章编号：1674-7860（2016）18-0015-04 证型：IDGA
【Abstract】Objective:To observe the clinical effect ofShugan Lipi Qufeng decoction combined with fexofenadine hydrochloride tabletsin treating chronic urticaria liver qi stagnation and spleen deficiencysyndrome. Methods: 60 patients with chronic urticaria liver qi stagnation andspleen deficiency syndrome, who were treated in the dermatological departmentof our hospital from April 2015 to December 2015, were randomly divided intothe observation group and the control group, with 30 cases in each group. Theobservation group received Shugan Lipi Qufeng decoction combined withfexofenadine hydrochloride tablets while the control group only receivedfexofenadine hydrochloride tablets. Two weeks formed one course and thetreatment lasted two courses. The clinical effect and the relief of systemicsymptoms and skin lesions were observed. Results: ①Thetotal effective rate of the observation group was 93.3%,which was significantly higher than that of the control group, 76.7%, the difference between twogroups was statistically significant (P< 0.05). ②After treatment, the general symptoms of the patient of two groups werecontrolled and the treatments were all effective, but the clinical effect of theobservation group was better than that of the control group. There weresignificant differences in indexes such as degree of itching, seizurefrequency, skin scratch disease, skin lesions distribution, duration and thesize and number of wheals before and after treatment (P < 0.05), the observation group was better than the controlgroup in improving the local symptoms and systemic symptoms and enhancing thequality of life of urticaria patients. ③Follow up 1 month afterstopping taking drug showed that the recurrence rate of the observation group and the control group was 13.3%and 30% respectively, the difference between two groups was statisticallysignificant (P < 0.05).Conclusion: Shugan Lipi Qufeng decoction combined with fexofenadinehydrochloride tablets had good clinical effect in treating chronic urticarialiver qi stagnation and spleen deficiency syndrome; it could relieve thesystemic symptoms and skin lesions and was of less adverse reaction and lowrecurrence rate, which was safe and reliable, therefore, it was worthy ofclinical promotion.
【Keywords】Chronicurticaria; Shugan Lipi Qufeng decoction; fexofenadine hydrochloride tablets