增液汤联合杞菊地黄丸治疗干眼病的临床研究
张明丽
（南阳医学高等专科学校，河南 南阳，473000)
中图分类号：R257 文献标识码：A 文章编号：1674-7860（2016）15-0098-03 证型：IDGB
【摘 要】目的：观察增液汤联合杞菊地黄丸对干眼病肝肾阴虚证的疗效。方法：将96例临床诊断为干眼病肝肾阴虚证患者随机分为观察组和对照组，对照组予以人工泪液治疗，观察组予以增液汤联合杞菊地黄丸治疗。结果：治疗前与治疗后组内比较，观察组BUT、SIt、FL均有一定程度的改善（P＜0.05），对照组结果同上。治疗后，与对照组比较，观察组BUT延长、SIt增多、FL降低，差异有统计学意义（P＜0.05）。两组疗效比较，观察组总有效率为95.8%，对照组总有效率为83.3%，两组疗效差异有统计学意义（P＞0.05）。结论：增液汤联合杞菊地黄丸能有效提高干眼病肝肾阴虚证患者泪液分泌功能、减轻其角膜炎症及角膜损伤，改善其症状和体征。
【关键词】干眼病；肝肾阴虚证；增液汤；杞菊地黄丸；人工泪液
【Abstract】Objective: To observe the clinical effectof Zengye Decoction combined with Qiju Dihuang Pill in treating ophthalmoxerosisof syndrome of yin deficiency of liver and kidney. Methods:96 patients with ophthalmoxerosis of syndrome of yin deficiency ofliver and kidney were randomly divided into the observation group and the controlgroup, the control group was treated with artificial tears while the observationgroup received Zengye Decoction combined with Qiju Dihuang Pill. Results:The comparison within the group beforetreatment and after treatment showed that BUT, SIt, FL of the observation grouphad certain degree of improvement (P＜0.05),it was the same with the control group. After treatment, compared with that of thecontrol group, BUT and SIt of the observation group increased, FL decreased,the difference was statistically significant (P＜0.05). The efficacy of the two groups wascompared, the effective rate of the observation group was 95.8% and that of thecontrol group was 83.3%, the difference between two groups was statisticallysignificant (P＞0.05). Conclusion: Zengye Decoctioncombined with Qiju Dihuang Pill could effectively improve the tear secretion ofpatients with ophthalmoxerosis of syndrome of yin deficiency of liver andkidney, it could reduce the inflammation of the cornea and corneal injury inaddition to improving the symptoms and signs.
【Keywords】Ophthalmoxerosis; Syndrome of yindeficiency of liver and kidney; Zengye Decoction; Qiju Dihuang Pill; Artificialtear mytear
doi:10.3969/j.issn.1674-7860.2016.15.047
参考文献：
[1]覃光辉,曲环汝,田雨,等.针刺干眼穴治疗干燥综合征干眼病临床观察[J]. 中医学报,2012,27(11) :1530-1531.
[2]陆燕,高卫萍.干眼病的中医经验方治疗研究[J].中医学报,2010,23(3):597-598.
[3]LempM A. New strategies in the treatment of dry-eye states[J].Cornea,1999(18):625.
[4]赵堪兴,杨培增.眼科学[M]. 7版.北京:人民卫生出版社,2008:81.
[5]曾庆华.中医眼科学[M].北京:中国中医药出版社,2003:148-149.
[6]崔鸿峥,马晓爽,姜双.自拟益气养阴散瘀方治疗干眼病的疗效及安全性分析[J].国际眼科杂志,2014,14(2):373-374.
[7]何陈亮,胡振仙,李永波.中医辨证联合人工泪液治疗干眼病的疗效[J].中华中医药学刊,2014,32(11):2753-2755.
[8]杨雪艳,何锦贤,梁先军,等.杞菊地黄汤内服联合超声雾化治疗肝肾阴虚型干眼症临床观察[J].新中医,2015(07):216-218.
[9]金红娟.石斛明目丸联合玻璃酸钠滴眼液治疗干眼病临床观察[J].新中医,2015,47(10):149-150.
[10]高媛,唐晓阳.杞菊地黄汤加减治疗干眼病临床研究[J].福建中医药,2014,45(1):12-13.
[11]邓芬.杞菊地黄汤治疗干眼病的临床观察[J].内蒙古中医药,2015,(03):10-11.
作者简介：
张明丽，女，医学硕士，讲师，主治中医师。主要从事中医教学及中医内科临床工作。研究方向：中医基础理论及老年病的中医药防治研究。
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