加味脱花煎提高药物流产完全流产率 及缩短阴道流血时间的临床观察
许英1 刘玉1 叶晨2※
（1. 广州中医药大学附属深圳市中医院，广东 深圳，518033；2.中医杂志社，北京，100700）
中图分类号：R271.43 文献标识码：A 文章编号：1674-7860（2016）15-0053-03 证型：BG
【摘 要】目的：研究中药加味脱花煎对提高药物流产完全流产率及缩短阴道流血时间的临床效果。方法：60例来我科行药物流产术的住院患者随机分为治疗组和对照组。两组均给予米非司酮合米索前列醇的标准药流方案，治疗组于服用米索前列醇2h后，服加减脱花煎。观察两组流产成功率及阴道流血持续时间。结果：治疗组完全流产27例，完全流产率为90.0%；对照组完全流产23例，完全流产率为76.7%，两组完全流产率比较差异有显著性（P＜0.05）。平均阴道流血时间治疗组（9.73±1.93）d，对照组（14.03±2.86）d，两组比较差异有显著性（P＜0.05）。结论：中药加味脱花煎配合米非司酮合米索前列醇药流方案可显著提高完全流产率，缩短阴道流血持续时间。
【关键词】药物流产；临床研究；中医药；脱花煎
【Abstract】Objectives:To investigate the efficiency of modified traditional Chinese Medicine (TCM)formula Modified Tuohua Decoction, on abortion ratio and colporrhagia inpatients with medical abortion. Methods: A total of 60 patients were randomlydivided into TCM group and control group. Patients in both TCM and controlgroup received standard therapy of mifepristone in combination withmisoprostol. At 2 hours post misoprostol administration, patients in TCM groupwere given Chinese herb medicine, modified Tuohua Decoction; whereas patientsin control group were given vehicle solution. Rate of successful abortion andduration of colporrhagia were observed for all subjects studied. Results: InTCM group, complete and successful abortion was observed in 27 cases (90.0%);whereas 23 cases in control group undergone successful abortion (76.7%).Successful abortion rate in TCM group was significantly higher than that in thecontrol group (P<0.05). Durationof colporrhagia in TCM group was significantly less than that in the controlgroup (9.73±1.93 days versus 14.03±2.86, P<0.05).Conclusions: TCM formula, Modified Tuohua Decoction is effective to improvesuccessful abortion rate and colporrhagia in patients with medical abortioninduced by combined therapy of mifepristone and misoprostol.
【Keywords】Medicalabortion; Clinical study; Traditional Chinese Medicine; ModifiedTuohua Decoction
doi:10.3969/j.issn.1674-7860.2016.15.026
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