滋补肝肾潜阳方治疗高血压病的临床研究
钱锋1 马英传2 张晓华1 孙颖1 于清华1
（1.吉林省中医药科学院，吉林长春，130021；2.长春中医药大学附属医院，吉林长春，130021）
中图分类号：R255.3 文献标识码：A 文章编号：1674-7860（2016）15-0049-03 证型：BDG
【摘 要】目的：观察滋补肝肾潜阳方治疗高血压病的临床疗效。方法：采用随机对照双盲方法，将72例高血压病患者分为两组，治疗组36例，对照组36例，治疗组脱落2例，对照组脱落5例。对照组给予西药降压药物基础治疗加配方颗粒模拟剂，治疗组（滋补肝肾潜阳方组）给予西药降压药物基础治疗加滋补肝肾潜阳方颗粒剂。两组连续治疗4周后进行临床疗效评价。结果：两组降压幅度比较，治疗组的24 h SBP、24 h DBP下降均优于对照组；降压有效率比较，治疗组总有效率为79.4%，对照组总有效率为48.4%，经统计学比较，差异有显著性意义（P＜0.05）。两组中医证候疗效比较，治疗组总有效率为85.3%；对照组总有效率为45.2%。滋补肝肾潜阳方组治疗后中医证候疗效明显，差异有显著性意义。两组疗效比较有显著性差异（P＜0.05）。结论：滋补肝肾潜阳方治疗高血压病肝肾阴虚、肝阳上亢证，可有效降低血压，改善临床症状。
【关键词】滋补肝肾潜阳方；高血压病；临床研究
【Abstract】Objective: To observe the clinical efficacy of Zibu GanshenQianyang prescription on hypertension. Methods: 72 cases of hypertensive wererandomly divided into a treatment group (36 cases) and a control groups (36cases) by using randomized, controlled, double-blind method. The treatmentgroup detached 2 cases and the control group detached 5 cases. The control groupwas treated with western medicine combined with dispensing granule of placebo,while the treatment group was treated with Zibu Ganshen Qianyang prescription based on western medicine. Aftercontinuous 4 weeks of treatment, the clinical effects were evaluated. Results: Twogroups of antihypertensive amplitude compared treatment group 24 hsbp, 24 hdbpwere better than that of the control group decreased; antihypertensiveefficiency compared, the total effective rate of the treatment group was 79.4%,while that of the control group was 48.39%, the difference was statisticallysignificant (P＜0.05). Two groups of TCMsyndrome curative effect comparison, the total effective rate of the treatmentgroup was 85.3%;while that of the control group was 45.2%. After treatment,Zibu Ganshen Qianyang prescription Group has accurate efficacy, and the differencewas significant. There was significant difference between the two groups (P＜0.05). Conclusion: Zibu GanshenQianyang prescription can treat deficiency of liver-yin and kidney-yin,hyperactivity of liver-yang type hypertension, effectively reducing bloodpressure and improving the clinical symptoms.
【Keywords】Zibu Ganshen Qianyang prescription; Hypertensive; Clinical research
doi:10.3969/j.issn.1674-7860.2016.15.024
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基金项目：
吉林省中医药管理局科技项目（项目编号：2014-Q24）。
作者简介：
钱锋，硕士,吉林省中医药科学院，副主任医师。E-mail：qfdoctor@126.com。
马英传，硕士,长春中医药大学附属医院，副主任医师。
张晓华，博士,吉林省中医药科学院，副主任医师。
孙颖，硕士,吉林省中医药科学院，主任医师。
于清华，博士，吉林省中医药科学院，副主任医师。
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